Gene

esyt2a

ID

ZDB-GENE-070912-588

Name

extended synaptotagmin-like protein 2a

Symbol

esyt2a Nomenclature History

Previous Names

fam62ba (1)
fc01a02
si:dkey-7l6.6 (1)
wu:fc01a02 (1)

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to have calcium ion binding activity and phospholipid binding activity. Predicted to be involved in endoplasmic reticulum-plasma membrane tethering and lipid transport. Predicted to localize to extrinsic component of cytoplasmic side of plasma membrane and intrinsic component of endoplasmic reticulum membrane. Orthologous to human ESYT2 (extended synaptotagmin 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With esyt2a Human Ortholog

No data available

Associated With esyt2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000008	C2 domain
Domain	IPR031468	Synaptotagmin-like mitochondrial-lipid-binding domain
Domain	IPR037733	Extended synaptotagmin, C2A domain
Domain	IPR037749	Extended synaptotagmin, C2B domain
Domain	IPR037752	Extended synaptotagmin, C-terminal C2 domain
Domain	IPR039010	Synaptotagmin, SMP domain
Family	IPR051634	Extended Synaptotagmin
Homologous_superfamily	IPR035892	C2 domain superfamily

Domain Details Per Protein

Protein	Length	C2 domain	C2 domain superfamily	Extended Synaptotagmin	Extended synaptotagmin, C2A domain	Extended synaptotagmin, C2B domain	Extended synaptotagmin, C-terminal C2 domain	Synaptotagmin-like mitochondrial-lipid-binding domain	Synaptotagmin, SMP domain
UniProtKB:E7FF26 InterPro	888
UniProtKB:E9QCP7 InterPro	867
UniProtKB:A0A8M9PPZ5 InterPro	901
UniProtKB:A0A8M2BIQ8 InterPro	922

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	esyt2a-201 (1) Ensembl	Ensembl	2,667 nt	Select Tool ZFIN BLAST
mRNA	esyt2a-202 (1) Ensembl	Ensembl	5,397 nt	Select Tool ZFIN BLAST
mRNA	esyt2a-203 (1) Ensembl	Ensembl	496 nt	Select Tool ZFIN BLAST
mRNA	esyt2a-204 (1) Ensembl	Ensembl	2,577 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations